Simplified exact analysis of case-referent studies: matched pairs; dichotomous exposure.

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Analysis of matched case-control studies.

There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a “matched analysis” is required. However, matching in a case-control study does not control for confounding by the matching factors; in fact it can introduce confounding by the matching factors even when...

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Estimability and estimation in case-referent studies.

The concepts that case-referent studies provide for the estimation of "relative risk" only if the illness is "rare", and that the rates and risks themselves are inestimable, are overly superficial and restrictve. The ratio of incidence densities (forces of morbidity)-and thereby the instantaneous risk-ratio-is estimable without any rarity-assumption. Long-term risk-ratio can be computed through...

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ژورنال

عنوان ژورنال: Journal of Epidemiology & Community Health

سال: 1983

ISSN: 0143-005X

DOI: 10.1136/jech.37.1.82